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The nuclear medicine department of the Institut Jules Bordet offers patients diagnostic tests of the functional or molecular type, as well as treatments with targeted molecular radiotherapy.  

The diagnostic tests differ from those carried out in the Radiology Department in that they involve the intravenous administration of substances labelled with radioactive isotopes, which specifically make it possible to identify the functionality or characteristic of an organ or of the cancer.

Therapeutic applications in nuclear medicine (often called “molecular radiotherapy”) use the same type of substance (tracer) specifically targeting the cancer tissue, but this substance is labelled with radioactive isotopes which emit therapeutic particles of the beta or alpha type enabling the destruction of the diseased cells.

Research projects

Project 1

Predicting the therapeutic result of 177Lu-octreotate (PRRT) using hybrid imaging in the case of refractory neuroendocrine tumours (LuMen)

Project 2

Somatostatin receptors imaging in relapsing and refractory multiple myeloma patients.

Project 3

Phase II prospective, multicentre study evaluating the utility of a an HER2-PET/CT combined with an FDG-PET/CT in identifying HER2 negative lesions that will not benefit from a new targeted treatment against HER2 : T-DM1 (ZEPHIR)
  • Project leader(s): Géraldine GebhartPatrick Flamen
  • Collaboration(s): Roche, Belgian and Dutch university hospital and centres  
  • Financing/Support : Roche

Project 4

Selective Internal Radiotherapy (SIRT) of colorectal hepatic metastases: prediction of the response

Project 5

An open-label study in which the diagnostic performance of an imaging agent coupled with a small amount of radioactive material is investigated for detection of clear cell renal carcinoma using CT/PET scans (ZIRCON study)

Project 6

MOLECULAR BIOMARKERS IN METASTATIC CASTRATE RESISTANT PROSTATE CANCER: PSMA EXPRESSION, METABOLIC ACTIVITY, AND CIRCULATING CELL-FREE DNA.

Our team

Head of Department
Prof Patrick Flamen

The team
Dr Carlos Artigas
Assistant Head of Clinic
Dr Géraldine GebhartAssistant Head of Clinic
Dr Ioannis KarfisAssistant Head of Clinic
Dr Elçin ÖzalpAssistant Head of Clinic
Dr Erwin WoffAssistant Head of Clinic
Dr Ivan Duran Derijckere, Resident

Radiophysicists (Department of Radiophysics)
Clémentine Marin, Radiophysicist 
Marie Christiane Yimo-Wadje (Physics control)
Gwennaëlle MarinRadiophysicist
Bruno Vanderlinden

Radiopharmacy
Prof Ghanem Ghanem

Zéna Wimana
Maxime Renguet
Adriana De Matos
Sara Coelho

Coordination of radionuclide treatments and thyroid checkups
Marie-Noëlle Gheeraert
Pauwel Thijs 
(thyroid cancer)

CoreLab molecular imaging (ORILAB)
Thomas Guiot, Ing

Research Unit
Zéna Wimana, Radiopharmacy/pre-clinical imaging
Wendy Delbart,
PhD Student/Research Assistant
Loubna Taraji Schiltz, Clinical Study Coordinator
Hugo Levillain, PhD Student in Medical Physics
Gabriela Critchi, Research Assistant

Secretaries
Jessie Toussaint
Anandi Henriet
Alyssa Hammouda (PET-Scan)

20/01/2020

 Scientific publications

Low 68Ga-PSMA PET/CT Uptake in Chronic Intramuscular Nodular Fasciitis.

Authors : Plouznikoff N, Artigas C, Karfis I, Flamen P
Year : 2020
Journal : Clin Nucl Med
Volume : 45
Pages : e41-e42

BONE HEALTH IN CANCER: ESMO CLINICAL PRACTICE GUIDELINES.

Authors : Coleman R, Hadji P, Body JJ, Santini D, Chow E, Terpos E, Oudard S, Bruland Ø, Flamen P, Kurth A, van Poznak C, Aapro M, Jordan K
Year : 2020
Journal : Ann Oncol

Systemic Sentinel Lymph Node Detection Using Fluorescence Imaging After Indocyanine Green Intravenous Injection in Colorectal Cancer: Protocol for a Feasibility Study.

Authors : Liberale G, Vankerckhove S, Bouazza F, Gomez Galdon M, Larsimont D, Moreau M, Bourgeois P, Donckier V
Year : 2020
Journal : JMIR Res Protoc
Volume : 9
Pages : e17976

COVID-19 Pneumonia Mimicking Immunotherapy-Induced Pneumonitis on 18F-FDG PET/CT in a Patient Under Treatment With Nivolumab.

Authors : Artigas C, Lemort M, Mestrez F, Gil T, Flamen P
Year : 2020
Journal : Clin Nucl Med
Volume : 45
Pages : e381-e382

Impact of <sup>68</sup>Ga-PSMA PET/CT in the treatment of prostate cancer: Initial experience in Spain.

Authors : Couñago F, Martínez-Ballesteros C, Artigas C, Díaz-Gavela AA, Gómez LLG, Lillo-García ME, Chicharo JR, Recio M, Maldonado A, Thuissard IJ, Andreu-Vázquez C, Sanz-Rosa D, Conde-Moreno AJ, Marcos FJ, García SS, Martínez-Salamanca JI, Carballido-Rodríguez J, Hornedo J, Cerro ED
Year : 2020
Journal : Rep Pract Oncol Radiother
Volume : 25
Pages : 405-411