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Radiotherapy remains one of the 3 pillars of treatment for patients affected by cancer. Half of all patients will undergo radiotherapy at one time or another. Radiotherapy may be used to treat cancer, improve quality of life and even to alleviate certain types of pain.

Radiotherapy uses the properties of ionizing radiation. Recent technological advances and a better understanding of the interaction between radiation and tumours has led to increasingly more effective equipment, in terms of both medical imaging (CT scan, MRI and PET scan) and radiotherapy.

Research projects


Project 1

CHEckpoint inhibition in combination with an immunoboost of External body Radiotherapy in Solid tumors: CHEERS-trial

Project 2

PEACE V: A randomized phase II trial for the Salvage Treatment of OligoRecurrent nodal prostate cancer Metastases (STORM)

Project 3

Phase IIIb randomized trial comparing irradiation plus long term adjuvant androgen deprivation with GnRH antagonist versus GnRH agonist plus flare protection in patients with very high risk localized or locally advanced prostate cancer. A joint study of the EORTC ROG and GUCG PEGASUS

Project 4

Radiation versus observation following surgical resection of atypical meningioma: a randomized controlled trial (The ROAM trial) EORTC protocol 1308-ROG-BTG
  • Project leader : Philippe Martinive
  • Funding : EORTC Cancer Research Fund / National Health System (UK)
  • Collaboration : EORTC


Project 5

A prospective randomized phase 2 study of dose and volume de-escalation in prophylactic nodal irradiation of contralateral neck by sentinel lymph nodes mapping in unilaterally node positive head and neck squamous cell carcinomas


Head of Department
Prof Dirk Van Gestel : ENT tumours, skin tumours, non-malignant tumours, sarcomas, breast tumours.

Senior Registrars
Dr Sylvie Beauvois : ENT tumours
Prof. Philippe Martinive : neurological, digestive and pediatric tumours
Prof. Luigi Moretti : digestive and thoracic tumours
Dr Catherine Philippson : breast tumours and intraoperative radiotherapy
Dr Martine Roelandts : thoracic tumours and lymphomas
Prof. Honorary Paul Van Houtte : thoracic and gynecological tumours, non-malignant tumours, curietherapy

The Team
Dr Adèle Baize : gynaecological tumours and curietherapy
Dr Christelle Bouchart : pancreatic and neurological tumours
Dr Alex De Caluwé : breast tumours, gynaecological tumours, curietherapy
Dr Antoine Desmet : breast, skin tumors, intraoperative radiotherapy and curietherapy
Dr Tatiana Dragan : ENT tumours, sarcomas (tumours of the central nervous system)
Dr François-Xavier Otte : digestive tumours, urological tumours
Dr Robbe Van den Begin : oligometastatic, urological and digestive tumours

Mrs Amaryllis N’Tumba
Mrs Carine Top
Mrs Carine Vandevelde


 Scientific publications

Prognostic impact of glioblastoma stem cell markers OLIG2 and CCND2.

Authors : Bouchart C, Trépant AL, Hein M, Van Gestel D, Demetter P
Year : 2020
Journal : Cancer Med
Volume : 9
Pages : 1069-1078

Retrospective evaluation of the safety of low-level laser therapy/photobiomodulation in patients with head/neck cancer.

Authors : Genot-Klastersky MT, Paesmans M, Ameye L, Kayumba A, Beauvois S, Dragan T, Van Gestel D, Lalami Y, Klastersky JA
Year : 2020
Journal : Support Care Cancer
Volume : 28
Pages : 3015-3022

The burden of low anterior resection syndrome on quality of life in patients with mid or low rectal cancer.

Authors : Bohlok A, Mercier C, Bouazza F, Galdon MG, Moretti L, Donckier V, El Nakadi I, Liberale G
Year : 2020
Journal : Support Care Cancer
Volume : 28
Pages : 1199-1206

Novel strategies using modern radiotherapy to improve pancreatic cancer outcomes: toward a new standard?

Authors : Bouchart C, Navez J, Closset J, Hendlisz A, Van Gestel D, Moretti L, Van Laethem JL
Year : 2020
Journal : Ther Adv Med Oncol
Volume : 12
Pages : 1758835920936093

Brachytherapy in Belgium in 2018. A national survey of the brachytherapy study group of the Belgian SocieTy for Radiotherapy and Oncology (BeSTRO).

Authors : Salembier C, De Hertogh O, Daisne JF, Palumbo S, Van Gestel D
Year : 2020
Journal : Radiother Oncol
Volume : 150
Pages : 245-252